Last TUESDAY every month at 3:00 – 4:00 pm CET

ESNI is launching a new initiative – Virtual ESNI Journal Club with Authors, featuring the last Tuesday of each month from 15:00-16:00 CET via Zoom. A volunteer junior researcher will present a selected article, while the main authors of the article will be available to discuss with you and address your questions. We wish to use the new digital reality to extend ESNI’s educational efforts to a broader audience and connect interested researchers to the latest Neuroimmunology findings.

If you have a suggestion for the article or wish to present it, please contact Maja Jagodic (maja.jagodic@ki.se) or Stine Overdal (esni@esni.org).

Upcoming Journal Clubs:

OCTOBER 29 @ 15:00 – 16:00 CET (OBS! CET is no longer summer time) – Targeting TGFβ-activated kinase-1 activation in microglia reduces CAR T immune effector cell-associated neurotoxicity syndrome – CLICK HERE FOR MORE INFORMATION

NOVEMBER 26 @ 15:00 – 16:00 CET – STAY TUNED

JANUARY 28 @ 15:00 – 16:00 CET – STAY TUNED

Past Journal Clubs:

SEPTEMBER 24, 2024 – Innate immune training restores pro-reparative myeloid functions to promote remyelination in the aged central nervous system
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AUGUST 27, 2024 – Multiple sclerosis endophenotypes identified by high-dimensional blood signatures are associated with distinct disease trajectories
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JUNE 25, 2024 – Optogenetic stimulation of mouse Hoxb8 microglia in specific regions of the brain induces anxiety, grooming, or both
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MAY 28, 2024 – The astrocyte-produced growth factor HB-EGF limits autoimmune CNS pathology
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APRIL 30, 2024 – Co-transplantation of autologous Treg cells in a cell therapy for Parkinson’s disease
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FEBRUARY 27, 2024 – Ineffective control of Epstein-Barr-virus-induced autoimmunity increases the risk for multiple sclerosis
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JANUARY 30, 2024 – The enteric nervous system relays psychological stress to intestinal inflammation
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NOVEMBER 28, 2023 Antigen recognition detains CD8+ T cells at the blood-brain barrier and contributes to its breakdown
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OCTOBER 31, 2023 Monocyte-derived IL-6 programs microglia to rebuild damaged brain vasculature
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SEPTEMBER 26, 2023 Age-induced alterations of granulopoiesis generate atypical neutrophils that aggravate stroke pathology
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AUGUST 29, 2023 Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease
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JUNE 27, 2023 Bacteria hijack a meningeal neuroimmune axis to facilitate brain invasion
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May 30, 2023 Impaired TIGIT expression on B cells drives circulating follicular helper T cell expansion in multiple sclerosis
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APRIL 26, 2023 Neural stem cell transplantation in patients with progressive multiple sclerosis: an open-label, phase 1 study
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MARCH 28, 2023 Cognate microglia–T cell interactions shape the functional regulatory T cell pool in experimental autoimmune encephalomyelitis pathology
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FEBRUARY 28, 2023 Antigen-specific depletion of CD4+ T cells by CAR T cells reveals distinct roles of higher- and lower-affinity TCRs during autoimmunity
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JANUARY 31, 2023 APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes
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NOVEMBER 29, 2022 Gut microbiome of multiple sclerosis patients and paired household healthy controls reveal associations with disease risk and course
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OCTOBER 25, 2022 Brain motor and fear circuits regulate leukocytes during acute stress
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SEPTEMBER 27, 2022 Bone marrow hematopoiesis drives multiple sclerosis progression
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AUGUST 30, 2022 Identification of four novel T cell autoantigens and personal autoreactive profiles in multiple sclerosis
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JUNE 28, 2022 Twin study reveals non-heritable immune perturbations in multiple sclerosis
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MAY 31, 2022 The lung microbiome regulates brain autoimmunity
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APRIL 26, 2022 Epigenomic priming of immune genes implicates oligodendroglia in multiple sclerosis susceptibility
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MARCH 29, 2022 Longitudinal analysis reveals high prevalence of Epstein-Barr virus associated with multiple sclerosis
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FEBRUARY 22, 2022 Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders
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JANUARY 25, 2022 Neurotoxic reactive astrocytes induce cell death via saturated lipids
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DECEMBER HAPPY HOLIDAYS!

NOVEMBER 30, 2021 Skin and gut imprinted helper T cell subsets exhibit distinct functional phenotypes in central nervous system autoimmunity
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OCTOBER 26, 2021 A lymphocyte-microglia-astrocyte axis in chronic active multiple sclerosis
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SEPTEMBER 28, 2021 Gut microbiota–specific IgA+ B cells traffic to the CNS in active multiple sclerosis
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AUGUST 31, 2021 Identifying CNS-colonizing T cells as potential therapeutic targets to prevent progression of multiple sclerosis
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JUNE 29, 2021 Distinct amyloid-β and tau-associated microglia profiles in Alzheimer’s disease
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MAY 25, 2021 Functional characterization of the dural sinuses as a neuroimmune interface
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APRIL 27, 2021 Propionic Acid Shapes the Multiple Sclerosis Disease Course by an Immunomodulatory Mechanism
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MARCH 30, 2021 Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis
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