11th ESNI Course | 4-7 July 2011

Program DAY ONE
Chairs: T. Olsson, L. Probert

Neuroinflammation and cellular responses in the CNS

09.00 – 09.45
Banking the brain – from resource to laboratory (S. Amor)

09.45 – 10.30
Neuropathology now! (H. Lassmann)

10.30 – 11.00
Coffee break

11.00 – 11.45
What’s really going on? Visualising neuroinflammation in vivo (M. Kerschensteiner)

11.45 – 12.30
Striking a balance – Innate vs adaptive immunity in neuroinflammation (H. Perry)

12.30 – 13.30
Lunch with the experts

Chairs: H. Perry, S. Amor

Genetics, Environmental factors and neuroinflammation

13.30 – 14.15
Emerging genetics in MS: a numbers game (S. Sawcer)

14.15 – 15.00
Gene-environment interactions In MS: triggers for disease induction (T. Olsson)

15.00 – 15.30
Coffee break

15.30 – 16.15
Where did it all start? Lessons from Lactose intolerance (M. Thomas)

16.15 – 17.00
Debate: funding research in the neuroimmunology of rare diseases is a luxury we can no longer afford
Chair: N. Scolding
Key speaker: H. Perry

DAY TWO
Chairs: E. Meinl, M.J. Sà

Disease Mechanisms and treatment strategies 1

09.00 – 09.45
Neurodegeneration and immunity: an intimate relationship. (R. Martini)

09.45 – 10.30
Neuroprotective strategies for inflammatory CNS diseases. (D. Baker)

10.30 – 11.00
Coffee break

11.00 – 11.45
T cells and autoimmune homeostasis (S. Anderton)

11.45 – 12.30
Sphingosine-1-phosphate pathways: therapeutic targets in autoimmune disease (A. Schubart)

12.30 – 13.30
Lunch with the experts

Chairs: R. Martini, A. Vincent

Disease Mechanisms and treatment strategies 2

13.30 – 14.15
B cell dependent mechanisms in neuroinflammatory diseases (E. Meinl)

14.15 – 15.00
Impact of immune re-education on CNS repair: lessons from alemtuzumab (A. Coles)

15.00 – 15.30
Coffee break

15.30 – 16.15
Using the immune system to treat Alzheimer’s disease (J. Nicoll)

16.15 – 17.00
Environmental factors – targets for preventative strategies in MS? (G. Ebers)

DAY THREE
Chairs: C. Linington, M.I. Leite

Humoral effector mechanisms in neurology

09.00 – 09.45
Autoantibodies in neurology; biomarkers to immunotherapeutic targets (C. Linington)

09.45 – 10.30
Channels and Receptors: critical targets in antibody mediated diseases. (A. Vincent)

10.30 – 11.00
Coffee break

11.00 – 11.45
Heteromeric lipid complexes: novel targets in neuroimmune disease. (H. Willison)

11.45 – 12.30
Neuromyelitis optica: from patient to model and back again (M. Bradl)

12.30 – 13.30
Lunch with the experts

This session is organized in collaboration with the European Federation of Neurological Societies (EFNS)

Chairs: N. Woodroofe, S. Barnett

Students led presentations and discussion

13.30 – 13.45
F. Brilot

13.45 – 14.00
K. Berger

14.00 – 14.15
K. Thewissen

14.15 – 14.30
C. Laterza

14.30 – 14.45
N. De Vocht

14.45 – 15.00
C. Lee

15.00 – 15.30
Coffee break

15.30 – 15.45
M. Karamita

15.45 – 16.00
A. Rupp

16.00 – 16.15
M. Kitic

16.15 – 16.30
G. Lovera

16.30 – 16.45
L. Garzetti

16.45 – 17.00
W. Van Rijs

DAY FOUR
Chairs: G. Martino, D. Karussis

Innate mechanisms and treatment strategies

09.00 – 09.45
Fc Receptors in neuroinflammation (J.L. Teeling)

09.45 – 10.30
Macrophages, Polarisation and Function (C. Goodyear)

10.30 – 11.00
Coffee break

11.00 – 11.45
Complement-based therapeutics in neurological diseases (C. Harris)

11.45 – 12.30
High dose iv Ig – mode of action and clinical applications (H-P. Hartung)

12.30 – 13.30
Lunch with the experts

Chairs: H. Willison, C. Harris

Stem cells and neuroinflammatory disease

13.30 – 14.15
Glial cell transplantation strategies in the CNS. (S. Barnett)

14.15 – 15.30
Neural stem cell transplantation; a therapeutic option. (G. Martino)

15.30 – 16.00
Coffee Break

15.30 – 16.15
Hematopoietic stem cell transplantation – an emerging strategy in autoimmunity? (P. Muraro)

16.15 – 17.00
Mesenchymal stem cells: where we are, where we go. (A. Uccelli)

Organizing Committee
• Linington, Christopher (United Kingdom)
• Martino, Gianvito (Italy)
• Hugh Willison (United Kingdom)

Chairs and Speakers
• Amor, Sandra (Amsterdam, the Netherlands)
• Anderton, Steve (Edinburgh, United Kingdom)
• Baker, David (London, United Kingdom)
• Barnett, Susan (Glasgow, United Kingdom)
• Bradl, Monika (Vienna, Austria)
• Coles, Alasdair (Cambridge, United Kingdom)
• Ebers, George (Oxford, United Kingdom)
• Goodyear, Carl (Glasgow, United Kingdom)
• Harris, Claire (Cardiff, United Kingdom)
• Hartung, Hans-Peter (Dusseldorf, Germany)
• Karussis, Dimitrios (Jerusalem, Israel)
• Kerschensteiner, Martin (Munich, Germany)
• Lassmann, Hans (Vienna, Austria)
• Leite, Maria Isabel (Oxford, United Kingdom)
• Linington, Christopher (Glasgow, United Kingdom)
• Martini, Rudolf (Würzburg, Germany)
• Martino, Gianvito (Milan, Italy)
• Meinl, Edgar (Martinsried, Germany)
• Muraro, Paolo (London, United Kingdom)
• Nicoll, James (Southampton, United Kingdom)
• Olsson, Tomas (Stockholm, Sweden)
• Perry, Hugh (Southampton, United Kingdom)
• Probert, Lesley (Athens, Greece)
• Sà, Maria José (Porto, Portugal)
• Sawcer, Stephen (Cambridge, United Kingdom)
• Schubart, Anna (Basel, Switzerland)
• Scolding, Neil (Bristol, United Kingdom)
• Teeling, Jessica (Southampton, United Kingdom)
• Thomas, Mark (London, United Kingdom)
• Uccelli, Antonio (Genoa, Italy)
• Vincent, Angela (Oxford, United Kingdom)
• Willison, Hugh (Glasgow, United Kingdom)
• Woodroofe, Nicola (Sheffield, United Kingdom)