Instanbul 2009

20 Febbraio 2009
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9th ESNI Course | 1-4 September 2009

Program DAY ONE
Chairs: G. Martino and A. Altintas

Neuroscience and neurobiology: basic aspects

9.00 – 9.45
The host defense of Drosophila melanogaster (D. Ferrandon)

09.45 – 10.30
Regulatory and effector T cells in the central nervous system (S.D. Miller)

9.45 – 10.30
Exploring the plant immune response (S. van Wees)

10.30 – 11.00
Coffee break

11.00 – 11.45
The inflammasome: a new entry (S. Drexler)

11.45 – 12.30
Autophagy in autoimmunity (F. Cecconi)

12.30 – 13.30
Lunch with the experts

13.30 – 14.15
The immunomodulatory role of neural stem cells (S. Pluchino)

14.15 – 15.00
Astrocytes, inflammation and neurodegeneration (T. Owens)

15.00 – 15.30
Coffee break

15.30 – 16.15
From Th1 to Th17: relevance for CNS autoimmunity (B. Becher)

16.15 – 17.00
The role of infection in CNS autoimmunity (M. Von Herrath)

DAY TWO
Chairs: L. Probert and R.Liblau

Basic and clinical aspects of neuroinflammation

9.00 – 9.45
Genetics of animal models of CNS inflammationì (M. Jagodic)

09.45 – 10.30
Innate immunity in the progression of inflammatory neurodegen (C. Dijkstra)

10.30 – 11.00
Coffee break

11:00 – 11:45
T cells in CNS tissue damage (R. Liblau )

11.45 – 12.30
Neuronal control of brain inflammation (L. Probert)

12.30 – 13.30
Lunch with the experts

13.30 – 14.15
Evolving neuropathological characterization of multiple sclerosis (H. Lassmann)

14.15 – 15.00
Ion channels as therapeutic targets of neurodegeneration (K. Smith)

15.00 – 15.30
Coffee Break

15.30 – 16.15
Dendritic cells and antigen presentation in the CNS during autoimmune disease (A. Vaknin-Dembinsky)

16.15 – 17.00
B cells in multiple sclerosis pathogenesis (F. Aloisi)

DAY THREE
Chairs: H. Willison and E. Battaloglu

Basic and clinical aspects of immune-mediated neuromuscular disorders

09.00 – 09.45
Mouse models of human neuromuscular disorders in vivo and ex vivo: a behavioural and physiological perspective (J. Plomp)

09.45 – 10.30
How to study the node of Ranvier: a cell biologist’s perspective (E. Peles)

10.30 – 11.00
Coffee break

11.00 – 11.45
Acquired peripheral neuropathies; from inflammation to demyelination (A. Quattrini )

11.45 – 12.30
Inflammatory components to genetic neuropathies: seeing is believing. (R. Martini)

12.30 – 13.30
Lunch with the experts

13.30 – 14.15
What’s new and clinically useful in the anti-nerve antibody field? (B. Jacobs )

14.15 – 15.00
Establishing novel diagnostic assays in a clinical neuroimmunology laboratory setting (A. Vincent)

15.00 – 15.30
Coffee break

15.30 – 16.15
Clinical research in motor nerve terminal and neuromuscular junction disorders (J. Verschuuren)

16.15 – 17.00
Developments in the scientific and clinical understanding of inflammatory myopathies (I. Lundberg)

DAY FOUR
Chairs: R. Karabudak and A. Siva

Pathogenesis and therapy of multiple sclerosis

09.00 – 09.45
Understanding multiple sclerosis pathogenesis: what animal models have taught us? (C. Linington)

09.45 – 10.30
Myelin repair in CNS: Role for guidance molecules (C. Lubetzki)

10.30 – 11.00
Coffee break

11.00 – 11.45
B cell immunology and multiple sclerosis: implications for treatment and data from clinical trials (A. Bar-Or)

11.45 – 12.30
What can we learn from treating multiple sclerosis? (O. Aktas)

12.30 – 14.00
Lunch with the experts Scientific thinking; science education and ethics (E. Kansu)

14.00 – 14.45
Potential new players on multiple sclerosis therapy: an introductory overview (R. Karabudak)

14.45 – 15.30
Lysophospholipids as mediators of immunity (O. Aktas)

15.30 – 16.00
Coffee break

16.00 – 16.45
Oral fingolimod and teriflunomide: mechanism of action, pre-clinical and clinical data in multiple sclerosis (G. Akman-Demir)

16.45 – 17.30
Rescue treatments: urgent treatments need for transitional stage multiple sclerosis (O. Kantarci)

Organizing Committee

• Rana Karabudak (Turkey)
• Dimitrios Karussis (Israel)
• Gianvito Martino (Italy)
• Tomas Olsson (Sweden)
• Lesley Probert (Greece)
• Hugh Willison (United Kingdom)

Chairs and Speakers

• Akman-Demir Gulsen (Istanbul, Turkey)
• Aktas, Orhan (Dusseldof, Germany)
• Aloisi, Francesca (Rome, Italy)
• Altintas, Ayse (Istanbul, Turkey)
• Bar-Or, Amit (Montreal, Canada)
• Battaloglu, Esra (Istanbul, Turkey)
• Becher, Burkhard (Zurich, Switzerland)
• Cecconi, Francesco (Rome, Italy)
• Dijkstra, Christine (Amsterdam, the Netherlands)
• Ferrandon, Dominique (Strasbourg, France)
• Hartung, Hans Peter (Dusseldorf, Germany)
• Jacobs, Bart(Rotterdam, the Netherlands)
• Jagodic, Maja (Stockholm, Sweden)
• Kansu, Emin (Ankara, Turkey)
• Kantarci, Orhun (Rochester, MN, United States)
• Karabudak, Rana (Ankara, Turkey)
• Lassmann, Hans (Vienna, Austria)
• Liblau, Roland (Toulouse, France)
• Linington, Chris (Glasgow, United Kingdom)
• Lubetzki, Catherine (Pairs, France)
• Lundberg, Ingrid (Stockholm, Sweden)
• Martini, Rudolf (Wuerzburg, Germany)
• Martino, Gianvito (Milan, Italy)
• Menu, Philippe (Lausanne, Switzerland)
• Owens, Trevor (Odense, Denmark)
• Peles, Elior (Rehovot, Israel)
• Plomp, Jaap (Leiden, the Netherlands)
• Pluchino, Stefano (Milan, Italy)
• Probert, Lesley (Athens, Greece)
• Quattrini, Angelo (Milan, Italy)
• Schwartz, Michal (Rehovot, Israel)
• Siva, Aksel (Istanbul, Turkey)
• Smith, Ken (Cambridge, United Kingdom)
• Vaknin-Dembinsky, Adi (Jerusalem, Israel)
• Van Wees, Saskia (Utrecht, the Netherlands)
• Verschuuren, Jan (Leiden, the Netherlands)
• Vincent, Angela (Oxford, United Kingdom)
• Von Herrath, Matthias (La Jolla, CA, United States)
• Willison, Hugh (Glasgow, United Kingdom)

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