15^th ESNI Course | June 1 – 4, 2015

DAY ONE
Chairs: G. Martino and P. Stourac

INNATE IMMUNE SYSTEM AND GLIA

09.00 – 09.45
Neuroinflammations (T. Owens)

09.45 – 10.30
CNS innate immune responses in chronic neurodegeneration (D. Gomez-Nicola)

10.30 – 11.00
Coffee Break

11.00 – 11.45
Microglia microvescicles as a new biomarker in neuroinflammation and neurodegeneration (R. Furlan)

11.45 – 12.30
Immune mechanisms of axonal injury (advanced imaging techniques) (M. Kerschensteiner)

12.30 – 13.30
LUNCH BREAK

Chairs: A. Vezzani and Hugh Willison

INNATE IMMUNE SYSTEM AND GLIA

13.30 – 14.15
Animal models of neuroinflammatory diseases: strenghts and weaknesses (L. Probert)

14.15 – 15.00
Neuroinflammation in AD (M. Heneka)

15.00 – 15.30
Coffee Break

15.30 – 16.15
Immune responses in the CNS in epilepsy (A. Vezzani)

16.15 – 17.00
Inflammation and accumulation of mitochondrial deficits as a cause of neurodegeneration (D. Mahad)

DAY TWO
Chairs: R. Furlan and A. Uccelli

ADAPTIVE IMMUNE RESPONSES IN THE CNS- T CELLS

09.00 – 09.45
Mechanisms of T cell pathogenesis (B. Becher)

09.45 – 10.30
Th17 and memory cells in CNS autoimmunity (T. Korn)

10.30 – 11.00
Coffee Break

11.00 – 11.45
CD8 T cell-mediated immunopathology in the CNS (R. Liblau)

11.45 – 12.30
Stem cells in immunomodulation and neuroprotection (A. Uccelli)

12.30 – 13.30
LUNCH BREAK

Chairs: D. Mahad and T. Korn

ADAPTIVE IMMUNE RESPONSES IN THE CNS- T CELLS

13.30 – 14.15
Neuronal regulation of neuroinflammation (S. Issazadeh-Navikas)

14.15 – 15.00
Paraneoplastic syndromes – update focused on new and emerging syndromes (P. Stourac)

15.00 – 15.30
Coffee Break

15.30 – 16.15
Treg in CNS autoimmunity and therapeutic perspectives (B. Salomon)

DAY THREE
Chairs: R. Ward and T. Owens

ADAPTIVE IMMUNE RESPONSES IN THE CNS- B CELLS

09.00 – 09.45
Neuroinflammation, ermerging roles for B cells and antibody in CNS disorders (C. Linington)

9.45 – 10.30
Neurobiology of multiple sclerosis (G. Martino)

10.30 – 11.00
Coffee Break

11.00 – 11.45
Immunopathology of B cell associated CNS disorders (H. Lassmann)

11.45 – 12.30
Neuroinflammation in neurodegenerative diseases including Alzheimer’s disease, Parkingson’s disease and Huntington’s disease (R. Ward)

12.30 – 13.30
LUNCH BREAK

Chairs: L. Probert and H. Willison

ADAPTIVE IMMUNE RESPONSES IN THE CNS- B CELLS

13.30 – 14.15
Human Ab and CNS demyelination, new methods for analyzing antibody specificities (J. Bennett)

14.15 – 15.00
B cell function and autoantibodies in MS (E. Meinl)

15.00 – 15.45
Pathogenic autoantibodies in human autoimmune encephalitis (J. Dalmau)

15.45 – 16.30
MS tissue and sample banks (S. Amor)

16.30 – 16.45
Coffee Break

Chairs S. Amor and H. Lassmann

DEBATE ON THE RELEVANCE OF MENINGEAL FOLLICLES IN MS

DAY FOUR
Chairs: N. Woodroofe and C. Linington

DISEASE

09.00 – 09.45
Narcolepsy (M. Tafti)

09.45 – 10.30
Autoimmune neuropathies (H. Willison)

10.30 – 11.00
Coffee Break

11.00 – 11.45
Treatment of CNS demyelinating disorders (E. Havrdova)

11.45 – 12.30
Immunological differences between NMO and MS / NMDA involvement

(Z. Illés)

12.30 – 13.30
LUNCH BREAK

Chairs: N. Woodroofe and P. Praksova

STUDENT PRESENTATIONS AND CLOSING LECTURE

13.30 – 13.45
The immunogenicity of amyloid beta oligomers and their role in macrophage-mediated inflammation (I. Dalgediene)

13.45 – 14.00
The novel role of ALCAM in neuroinflammation and BBB homeostasis

(M-A. Lécuyer)

14.00 – 14.15
Stressed oligodendrocytes trigger microglia activation a key event in early multiple sclerosis lesion formation (L. Peferoen)

14.15 – 14.30
Chemokine expression and migration of immune cells in the central nervous system in viral neuroinflammation, with focus on regulatory T cells (L. Lind)

14.30 – 14.45
TSPO-PET imaging reveals that anti-VLA-4 treatment leads to reduced microglial activation in focal rodent EAE (S. Vainio)

CLOSING LECTURE

14.45 – 15.30
Gut microbioma and autoimmunity-current status and perspectives (G. Krishnamoorthy)