6th Esni Course | 12-15 September 2005
Program DAY ONE
Chairs: Gianvito Martino (Italy) and Ariel Miller (Israel)
Methods in Neuroimmunology
09.00 – 09.45
Mechanisms of tissue injury in human inflammatory brain diseases
Hans Lassmann, Austria
09.45 – 10.30
Regulation of the immune response within the central nervous system
Jack Antel, Canada
10.30 – 11.00
Coffee break
11.00 – 11.45
Immunoregulation of Th1 and Th2 responses in neuroinflammation
(Lesley Probert, Greece)
11.45 – 12-30
Cholinergic signals: a bridge between the nervous and the immune systems (Hermona Soreq, Israel)
12.30 – 14.30
Lunch with the expert
14.30 – 15.15
Antibody assays for neuronal targets
(Angela Vincent, UK)
15.15 – 16.00
Biomarkers in neuroinflammation: the role of cell surface molecules, cytokines and proteases (Ariel Miller, Israel)
16.00 – 16.30
Coffee break
16.30 – 17.15
Pharmacogenetic approaches in neuroimmunology
(Iris Grossmann, USA)
17.15 – 18.00
Animal models in neuroimmunological diseases
(Nikolas Grigoriadis, Greece)
DAY TWO
Chairs: Piet Stinissen (Belgium) and Nikolas Grigoriadis (Greece)
Immunointervention
09.00 – 09.45
The immunological homunculus (Irun COHEN, Israel )
09.45 – 10.30
Specificity and degeneracy of T cell recognition in CNS autoimmunity: considerations for the development of antigen and TCR specific therapies (Bernard Hemmer, Germany)
10.30 – 11.00
Coffee break
11.00 – 11.45
DNA vaccination with pro-inflammatory cytokines (Nathan Karin, Israel)
11.45 – 12.30
DNA vaccination with encephalitogenic epitopes in autoimmune disease (Anna Lobell, Sweden)
12.30 – 14.30
DLunch with the expert
14.30 – 15.15
Neuroprotective and anti-inflammatory therapeutic approach in experimental stroke (Dirk Hermann, Switzerland)
15.15 – 16.00
T cell receptor peptide therapy in myasthenia gravis (Sylvia Cohen-Kaminsky, France)
16.00 – 16.30
Coffee break
16.30 – 17.15
Neuroinflammation in Alzheimer’s disease as a possible window for intervention? (Tony Wyss-Coray, USA)
17.15 – 18.00
Statins: immunomodulatory effects and therapeutic potential for multiple sclerosis (Hans-Peter Hartung, Germany)
DAY THREE
Chairs: Tomas Olsson (Sweden) and Nils Erik Gilhus (Norway)
Genetics
09.00 – 09.45
Non-MHC gene influences in rat neuroinflammation (Maja Jagodic, Sweden)
09.45 – 10.30
Gene positioning in rodent inflammation (Rikard Holmdahl, Sweden)
10.30 – 11.00
Coffee break
11.00 – 11.45
MHC gene influences and function in neuroinflammation (Robert Weissert, Gerrmany)
11.45 – 12.30
HLA and human neuroinflammation (Jan Hillert, Sweden)
12.30 – 15.00
Lunch with the expert
15.00 – 15.45
Non-MHC genetics in humans (Steven Sawcer, UK)
15.45 – 16.30
Genetics of neurodegeneration (Fredrik Piehl, Sweden)
16.30 – 17.00
Coffee break
17.00 – 17.45
Genetics of peripheral neuropathies (Christian Vedeler, Norway)
17.45 – 18.30
Genetics of inflammation (ApoE and more) in models of neurodegeneration (Danny Michaelson, Israel)
20.30 – 23.00
Social Dinner
DAY FOUR
Chairs: R. Dimitris Karussis (Israel) and Ioannis Mylonas (Greece)
Infection and autoimmunity
09.00 – 09.45
Overview of molecular mimicry and post-infectious mechanisms (Steven Miller, USA)
09.45 – 10.30
Mechanisms of mimicry in human diseases: the post streptococcal syndrome (PANDAS) paradigm (Dimitri Karussis, Israel)
10.30 – 11.00
Coffee break
11.00-11.45
The significance of LPS and bacterial antigens in neurological para-infectious syndromes: the paradigm of Guillaine Barre Syndrome (Itzhak Wirguin, Israel)
11.45-12.30
Potential role of bacterial superantigens as triggers of autoimmune demyelination (Piet Stinissen, Belgium)
12.30-15.00
Lunch with the expert
15.00 – 15.45
Endogenous retroviruses and multiple sclerosis (Tomasz Brudek, Denmark)
15.45 – 16.30
HIV and immune mediated neurological syndromes: mechanisms (Israel Steiner, Israel)
16.30 – 17.00
Coffee break
17.00 – 17.45
Post-polio syndrome: facts and myths (Tomas Olsson, Sweden)
17.45 – 18.00
Neuro-Lyme; what’s new (Markus Fritzchke, Switzerland)
Organizing Committee
• Nils Erik Gilhus (Norway)
• Nikolas Grigoriadis (local organizer, Greece)
• Dimitrios Karussis (organizer, Israel)
• Gianvito Martino (Italy)
• Ariel Miller (organizer, Israel)
• Ioannis Milonas (local organizer, Greece)
• Tomas Olsson (Sweden)
• Piet Stinissen (Belgium)
Chairs and Speakers
• Antel, Jack (Montreal, Canada)
• Brudek, Tomasz (Aarhus, Denmark)
• Cohen, Irun (Rehovot, Israel)
• Cohen-Kaminsky, Sylvia (Le Plessis, France)
• Fritzchke, Markus (Switzerland)
• Gilhus, Nils Erik (Bergen, Norway)
• Grigoriadis, Nikolas (Thessaloniki, Greece)
• Grossman, Iris (Durham, United States)
• Hartung, Hans-Peter (Duesseldorf, Germany)
• Hemmer, Bernard (Duesseldorf, Germany)
• Hermann, Dirk (Zurich, Switzerland)
• Hillert, Jan (Stockholm, Sweden)
• Holmdahl, Rikard (Lund, Sweden)
• Jagodic, Maja (Stockholm, Sweden)
• Karin, Nathan (Haifa, Israel)
• Karussis, Dimitrios (Jerusalem, Israel)
• Lassmann, Hans (Viena, Austria)
• Lobell, Anna (Stockholm, Sweden)
• Martino, Gianvito (Milan, Italy)
• Michaelson, Daniel (Tel Aviv, Israel)
• Miller, Steven (Chicago, United States)
• Miller, Ariel (Haifa, Israel)
• Milonas, Ioannis (Thessaloniki, Greece)
• Olsson, Tomas (Stockholm, Sweden)
• Piehl, Fredrik (Stockholm, Sweden)
• Probert, Lesley (Athens, Greece)
• Sawcer, Steven (United Kingdom)
• Soreq, Hermona (Jerusalem, Israel)
• Steiner, Israel (Jerusalem, Israel)
• Stinissen, Piet (Diepenbeek, Belgium)
• Vedeler, Christian (Bergen, Norway)
• Vincent, Angela (Oxford, United Kingdom)
• Weissert, Robert (Tuebingen, Germany)
• Wirguin, Itzhak (Beer-Sheva, Israel)
• Wyss-Coray, Tony (Stanford, United States)
